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Frequency estimation OF tuberculosis with extensively drug resistance in patients of diff erent registration groups

Abstract

Aim: to estimate the share of tuberculosis with extensively drug resistance in TB patients with a different history of treatment in Russian Federation.
Materials. Тhe results of the survey of patients with multidrugresistant tuberculosis in public (24,464) and penitentiary (1,780) health care were studied.
Results. The share of cases of extensively drug-resistant tuberculosis among cases of multidrug-resistant tuberculosis was 13.6% in public and 11.0% in the penitentiary sector, which is higher than the global rates. In homogeneous registration groups in the civil and penitentiary sector, it is comparable, and for new cases it is 8.0% (95% CI 7.4–8.5%), for cases of relapse - 13.5% (95% CI 12.3–14.7%), in other retreatment cases – 17.4% (95% CI 15.7–19.1%). The risk of extensively drug-resistant Mycobacterium tuberculosis in cases of re-treatment of 1.7 (in the cases of tuberculosis relapse) – 2.2 (in the other retreatment cases) times higher than that of new TB cases.
Conclusion. The obtained results substantiate the expediency of separation of the flows of newly diagnosed TB patients and retreatment TB cases, incl. multidrug-resistant TB.

About the Authors

S. A. Sterlikov
ФГБУ «Центральный НИИ организации и информатизации здравоохранения» Минздрава России
Russian Federation


L. I. Rusakova
ФГБНУ «Центральный НИИ туберкулеза»
Russian Federation


E. M. Belilovsky
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


S. B. Ponomarev
ФКУ «НИИ Федеральной службы исполнения наказаний России», Ижевский филиал, Республика Удмуртия, г. Ижевск.
Russian Federation


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Review

For citations:


Sterlikov S.A., Rusakova L.I., Belilovsky E.M., Ponomarev S.B. Frequency estimation OF tuberculosis with extensively drug resistance in patients of diff erent registration groups. Tuberculosis and socially significant diseases. 2018;(1):6-11. (In Russ.)

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ISSN 2413-0346 (Print)
ISSN 2413-0354 (Online)