The case of successful treatment extensively drug-resistant tuberculosis patient with concomitant advanced breast carcinoma (clinical case)
Abstract
In a clinical case, a successful treatment of pulmonary tuberculosis caused by extensively drug-resistant mycobacteria in a patient with oncology presented. The peculiarity of this case can be called extensively drug-resistant tuberculosis of a young patient with advanced breast carcinoma, without pronounced clinical symptoms, socially preserved, fluorographically examined not annually. The presented clinical case demonstrates the relevance of the topic under discussion. Treatment of drug-resistant tuberculosis is an urgent problem for the whole world. The appointment of the V chemotherapy regimen to the patient, with the inclusion of linezolid, perchlozone and bedaquiline in the complex therapy, made it possible to achieve stabilization of the patient’s condition in the shortest possible time, a pronounced positive clinical and radiological dynamics of a specific process in the lungs with extensive drug resistance of mycobacterium tuberculosis.
About the Authors
O. V. LushinaRussian Federation
M. V. Pavlova
Russian Federation
L. I. Archakova
Russian Federation
N. V. Sapozhnikova
Russian Federation
I. V. Chernokhaeva
Russian Federation
References
1. Васильева И.А., Самойлова А.Г. Современные подходы к химиотерапии туберкулеза легких // Пульмонология. – 2014. – № 3. – С. 108-112.
2. Туберкулез у взрослых: клинические рекомендации. – Российское общество фтизиатров, 2020. [Электронный ресурс]. URL: http://cr.rosminzdrav.ru/#!/recomend/943. (Дата обращения 01.08.2020).
3. Федеральные клинические рекомендации по диагностике и лечению туберкулеза органов дыхания с множественной и широкой лекарственной устойчивостью возбудителя. – 3-е изд. – Российское общество фтизиатров, 2015. – 68 с.
4. Эпидемическая ситуация по туберкулезу в Российской Федерации в 2018 г. – Федеральный центр мониторинга противодействия распространению туберкулеза в Российской Федерации. [Электронный ресурс]. URL: https://mednet.ru/images/materials/CMT/2018_god_tuberkulez_epidsituaciya.pdf (Дата обращения 01.08.2020).
5. Global tuberculosis report 2019, Geneva: World Health Organization, 2019.
6. Nunn A.J., Rusen I.D., Van Deun A. et al. Evaluation of a standardized treatment regimen of anti-tuberculosis drugs for patients with multi-drug-resistant tuberculosis (STREAM): study protocol for a randomized controlled trial // Trials, 2014. – Vol. 15. – N. – 1. [353].
7. https://doi.org/10.1186/1745-6215-15-353.
Review
For citations:
Lushina O.V., Pavlova M.V., Archakova L.I., Sapozhnikova N.V., Chernokhaeva I.V. The case of successful treatment extensively drug-resistant tuberculosis patient with concomitant advanced breast carcinoma (clinical case). Tuberculosis and socially significant diseases. 2020;(3):63-67. (In Russ.)