Patient with tuberculosis/COVID-19 co -infectio n in early po stoperativ e period after pneumonectomy and thoraco myoplasty

Abstract

Clinical case of COVID-19/TB co-infection in 47 y. o. female with TB, diagnosed in 2005, after partial right lung resection in 2006 and 2012. In April 2019 TB relapse with XDR detected, in February 2020 – right-side pneumonectomy for fibrotic multichamber cavern. 03.04.2020 г. – right-side seven-rib thoracomyoplasty due to the right main bronchus stump failure. 10.04.2020 – intoxication and severe shortness of breath need for oxygen support. 12.04.2020 – positive smear from nasooropharynx for RNA of SARS-Cov-2. CT 13.04.2020 – in the singleleft lung severe viral pneumonia (CT-3). Therapy: lopinavir/ritonavir 400 mg + 100 mg every 12 hours for 14 days with recombinant alfa-interferon intranasal for 5 days. On 7th day of the treatment – the clinical improvement, normalization of body temperature, исчезла необходимость респираторной поддержки. CT on 7th and 14th days of treatment – positive changes up to complete resorption of pneumonia. On 11th and 14th days, – negative smears from nasooropharynx for SARS-Cov-2. The TB-treatment continued.