DRUG SUSCEPTIBILITY MYCOBACTERIA WITH TEST SYSTEMS «SENSITITRE»
Abstract
Timely administration of appropriate treatment reduces the level and rate of emergence of resistant strains of mycobacteria. Therefore, the actual is to develop methods for early and reliable drug susceptibility testing. With the help of test systems Sensititre MycoTB
studied 149 strains of M. tuberculosis, isolated from respiratory material patients with chronic forms of tuberculosis. With the help of test systems Sensititre SLOMyco RAPMyco were tested 471 NTMB strain isolated from patients with suspected tuberculosis or mycobacteriosis belonging to species: MAC – 139, M. kansasii – 57, M. xenopi – 59, M. fortuitum group – 170 and M. chelonae group – 46.
The results allowed to conclude that the test system Sensititre have advantages associated with the standardization process and to determine the extent susceptibility/resistant isolates of mycobacteria, as well as the possibility of obtaining information about the spectrum of drug sensitivity to a large number of drugs in the short term.
About the Authors
M. V. MakarovaRussian Federation
Yu. D. Isaeva
Russian Federation
E. N. Hachaturyants
Russian Federation
V. I. Litvinov
Russian Federation
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Review
For citations:
Makarova M.V., Isaeva Yu.D., Hachaturyants E.N., Litvinov V.I. DRUG SUSCEPTIBILITY MYCOBACTERIA WITH TEST SYSTEMS «SENSITITRE». Tuberculosis and socially significant diseases. 2013;(2):30-34. (In Russ.)