COLONOSCOPY IN ABDOMINAL TUBERCULOSIS DIAGNOSTICS
Abstract
Since 2010 till 2012 76 colonoscopies were performed in 63 patients (22-77 years old, 63,5% males and 36,5% females), suspected as abdominal tuberculosis (AT). Pulmonary tuberculosis was diagnosed in 49 (77,7%) patients, AT without pulmonary tuberculosis was suspected in 5 (7,9%). 49,2% patients were HIVinfected. Visual evidence of intestinal tuberculosis were observed in 74,6% patients, histological findings (epithelioid cell granuloma, acid-fast mycobacteria) – in 38,1%, adenocarcinoma of the colon – in 3,2%, CMV-colitis – in 6,4%, nonspecific colitis – in other 58,7% cases. Luminescent microscopy of intestinal specimen removed from ulcers revealed M.tuberculosis (MBT) in 27,0%. Bacteriologic verification on solid media was obtained in 33,3% including 4 patients with negative result of luminescent microscopy. DNA of MBT was detected by polymerase chain reaction in 44,4% cases. So, colonoscopy is fast, cheap and reliable method of intestinal tuberculosis diagnostics allowing prove the origin of the disease in over 75% patients.
About the Authors
M. N. Reshetnikov
ГКУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation
Russian Federation
M. V. Matrosov
ГКУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation
Russian Federation
A. G. Antipov
ГКУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation
Russian Federation
R. V. Malzev
ГКУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation
Russian Federation
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Review
For citations:
Reshetnikov M.N., Matrosov M.V., Antipov A.G., Malzev R.V. COLONOSCOPY IN ABDOMINAL TUBERCULOSIS DIAGNOSTICS. Tuberculosis and socially significant diseases. 2014;(3):39-42. (In Russ.)
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