Assessment of risk factors in the foci of tuberculosis in the Perm Region

Abstract

In the Perm Region, with a decrease in the total burden of tuberculosis in children, in 40.5% of cases there is information on the contact with TB patients, including patients with comorbidity of HIV + tuberculosis and drug-resistant pathogen. The assessment of epidemiological characteristics and quality of diagnosis of tuberculosis in the foci of infection has been performed. It has been found that the average ratio of the number of contacts to TB patients does not exceed 1,5 : 1, and 31.5% of the total number of contacts are children and teenagers. Of these 40.4% are children from the foci of MBT+, including 7.8% of cases with multi- and 3.4% of cases with extensively drug-resistant pathogen. At the same time, in 1.2% and 0.6% of cases, respectively, this risk factor is accompanied by the
presence of HIV infection in patients. These children are particularly at risk, so the obligatory diagnostic methods include application of tuberculosis recombinant allergen, CT of chest, full, adequate and well-controlled preventive treatment taking into account resistance in the focus. In addition, final disinfection in the foci of TB infection should be conducted.