Non-specific bacterial and fungal infection of the respiratory tract in patients with tuberculous pleurisy
https://doi.org/10.54921/2413-0346-2022-10-1-8-12
Abstract
Rationale. The fact of colonization of the respiratory tract by nonspecific microbial flora in pulmonary tuberculosis is known, but there is no data on the features of infection of the respiratory tract with nonspecific microbial and fungal flora in tuberculous exudative pleurisy (TEP).
Purpose. To study the spectrum and antibiotic resistance of nonspecific microflora of the respiratory tract in patients with TEP.
Materials and methods. The analysis of the results of microbiological studies of sputum and bronchial washings of 238 patients with TEP, including 162 men and 76 women aged 18 to 88 years, was carried out.
Results. Various types of nonspecific microflora in the sputum of patients were detected by culture on nutrient media in 176 (73.95 %) of 238 patients with TEP. Only microbial flora was isolated in 54 (30.68 %), only fungal - in 59 (33.52 %) and association of microbial and fungal flora – in 63 (35.80 %) of 176 patients. The analysis showed the predominance of Streptococcus pyogenes (32.11%), Escherichia coli and Klebsiella pneumonia (11.68 % each). The microbial flora in 29.9 % of cases had DRs to broad-spectrum antibiotics, in 11.7 % to drugs with antituberculosis activity.
About the Author
N. A. Stogova
Voronezh State Medical University named after N.N. Burdenko Ministry of Health of the Russian Federation
Russian Federation
Russian Federation
Department of Phthisiology
Voronezh
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Review
For citations:
Stogova N.A. Non-specific bacterial and fungal infection of the respiratory tract in patients with tuberculous pleurisy. Tuberculosis and socially significant diseases. 2022;10(1):8-12. (In Russ.) https://doi.org/10.54921/2413-0346-2022-10-1-8-12
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