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The study of drug susceptibility of the slow-growing mycobacterium M. xenopi

Abstract

The drug sensitivity of 74 strains of slow-growing Mycobacterium species M. xenopi was studied using the method of serial microdilutions – Sensititre SlowMyco (TREK DIAGNOSTIC Systems Ltd., UK).
It was found that this species of NTM is more often resistant to «basic» anti-tuberculosis drugs, and to other chemotherapy drugs used for the treatment of relevant mycobacterioses, according to different authors, may be sensitive or resistant.
The results of the studies described in this paper confirm these positions and give a more detailed description of the degree of sensitivity/ resistance of M. xenopi to the main drugs.

About the Authors

M. V. Makarova
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


E. N. Khachatourians
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


M. A. Krasnova
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


K. Yu. Galkina
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


L. D. Guntupova
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


A. O. Chizhova
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


V. I. Litvinov
ГБУЗ «Московский городской научно-практический центр борьбы с туберкулезом Департамента здравоохранения города Москвы»
Russian Federation


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Review

For citations:


Makarova M.V., Khachatourians E.N., Krasnova M.A., Galkina K.Yu., Guntupova L.D., Chizhova A.O., Litvinov V.I. The study of drug susceptibility of the slow-growing mycobacterium M. xenopi. Tuberculosis and socially significant diseases. 2018;(3):26-31. (In Russ.)

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