EPIDEMIOLOGY, CLINIC AND DIAGNOStIcS OF SARCOIDOSIS IN THE REPUBLIC OF BELARUS
Abstract
The article is devoted to the analysis of the structure of morbidity, disability, diagnostic features and clinical course of sarcoidosis. From 1977 to 2012 the incidence of sarcoidosis in the Republic of Belarus increased 6.2 times and reached a level of 8.0 per 100,000 population (since 2013, information on the incidence of sarcoidosis has not been included in the list of mandatory reporting of TB services). In 2019 the incidence rate will reach the level of 10.2 ± 0.34 per 100,000 populations according to the forecast. The primary disability rate is reduced by 2.4% per year. The patients with a minor and asymptomatic course of sarcoidosis prevail in Belarusian population (80.2% in 2005–2015). Stage II of sarcoidosis dominates (76%, p = 0.002). Extrapulmonary manifestations of sarcoidosis are diagnosed seldom (15.7% of cases). An algorithm for sarcoidosis diagnosing has been developed with the inclusion of new prediction criteria in the survey program (total lipid phosphorus level in induced sputum < 90.5 μmol P / L) in combination with a 6-minute walk distance < 425 m) and disease activity (level of tumor necrosis factor-α in induced sputum > 70 ng/ml).
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Review
For citations:
Baradzina H.L. EPIDEMIOLOGY, CLINIC AND DIAGNOStIcS OF SARCOIDOSIS IN THE REPUBLIC OF BELARUS. Tuberculosis and socially significant diseases. 2019;(2):16-23. (In Russ.)
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