A clinical case of Acute kidney injury associated with hypercalcemia in A patient with generalized tuberculosis
https://doi.org/10.54921/2413-0346-2025-13-3-66-71
Abstract
Granulomatous inflammation in tuberculosis is a risk factor for hypercalcemia. In hypercalcemia caused by tuberculosis, calcium levels return to normal after anti-tuberculosis therapy; however, high calcium levels are a risk factor for renal damage.
A clinical case of renal damage caused by hypercalciemia in a patient with generalized tuberculosis is presented. The examination revealed a diagnosis of tuberculous meningoencephalitis, miliary pulmonary tuberculosis, tuberculosis of the intrathoracic lymph nodes in the abscessing phase, tuberculosis of the peripheral (supraclavicular, subclavian, anterior cervical) lymph nodes in the infiltration and abscessing phase, and tuberculosis of the bone marrow. The blood calcium level upon admission was 3.86 mmol/l, serum creatinine was 255 μmol/l. During the course of anti-tuberculosis, infusion and symptomatic therapy, normalization of the calcium level and restoration of renal function, positive dynamics of the tuberculosis process were achieved.
Conclusion. Timely administration of infusion, symptomatic, anti-tuberculosis therapy allows normalizing calcium levels and restoring renal function in a patient with renal damage caused by capercalcemia in a patient with tuberculosis.
About the Authors
D. A. Vishnevskii
Moscow Research and Clinical Center for Tuberculosis Control of the Moscow City Health Department
Россия
Россия
Moscow
O. V. Rodina
Moscow Research and Clinical Center for Tuberculosis Control of the Moscow City Health Department
Россия
Россия
Moscow
R. M. Chotchaev
Moscow Research and Clinical Center for Tuberculosis Control of the Moscow City Health Department ; The Russian Medical Academy of Continuing Professional Education of the Ministry of Health of the Russian Federation ; Peoples’ Friendship University of Russia named after Patrice Lumumba
Россия
Россия
Moscow
O. A. Novikova
Moscow Research and Clinical Center for Tuberculosis Control of the Moscow City Health Department
Россия
Россия
Moscow
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Review
For citations:
Vishnevskii D.A., Rodina O.V., Chotchaev R.M., Novikova O.A. A clinical case of Acute kidney injury associated with hypercalcemia in A patient with generalized tuberculosis. Tuberculosis and socially significant diseases. 2025;13(3):66-71. (In Russ.) https://doi.org/10.54921/2413-0346-2025-13-3-66-71
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