Residual changes after tuberculosis and chronic obstructive pulmonary disease
https://doi.org/10.54921/2413-0346-2022-10-2-34-39
Abstract
The aim of the study. To identify differences in the course of COPD, which occurred after the cure of tuberculosis in a patient with the formation of residual changes, and COPD, which occurred before the detection of tuberculosis in the patient, after the regression of mycobacterial infection.
Materials and methods. With the help of computer number generation, study groups 1 (patients who did not have a history of COPD before tuberculosis was detected) and 2 (patients with a history of COPD) were identified, 94 patients in each group.
The results of the study. In group 1 patients, there is a decrease in FEV1 in the range of 70-80% in 19.1% and in the range of 60-69% in 40.4% of cases, while in 7.4% there is an absolute increase in FEV1 per 200 ml and a bronchodilation coefficient of more than 12% according to the results of the bronchodilation test, and the ratio of FEV1 /VEL of less than 75% was noted in 69.1% of cases. On CT scans in group 2, bronchiectasis and bullae are more common. Progression of obstruction in the form of a decrease in FEV1 per year by an average of 90-105 ml in 61.7% of cases is observed in group 2 patients. Conclusion. The results obtained do not confirm the data on a more severe course of obstructive disease that developed after the formation of post-tuberculosis changes. Patients who had COPD before the detection of tuberculosis, in the presence of residual post-tuberculosis changes in the lungs, more often demonstrated indicators of the irreversible course of the disease.
About the Authors
A. Yu. Chernikov
ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России, кафедра клинической иммунологии, аллергологии и фтизиопульмонологии
Russian Federation
Russian Federation
A. V. Dyakov
ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России, кафедра клинической иммунологии, аллергологии и фтизиопульмонологии
Russian Federation
Russian Federation
K. D. Rotenko
ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России, кафедра клинической иммунологии, аллергологии и фтизиопульмонологии
Russian Federation
Russian Federation
A. A. Ivanova
ФГБОУ ВО «Курский государственный медицинский университет» Минздрава России, кафедра клинической иммунологии, аллергологии и фтизиопульмонологии
Russian Federation
Russian Federation
N. V. Rachina
ОБУЗ «Областной клинический противотуберкулезный диспансер» Комитета здравоохранения Курской области
Russian Federation
Russian Federation
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Review
For citations:
Chernikov A.Yu., Dyakov A.V., Rotenko K.D., Ivanova A.A., Rachina N.V. Residual changes after tuberculosis and chronic obstructive pulmonary disease. Tuberculosis and socially significant diseases. 2022;10(2):34-39. (In Russ.) https://doi.org/10.54921/2413-0346-2022-10-2-34-39
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